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The objective of this study is to describe the prevalence of symptoms of gastro-oesophageal reflux disease (GERD) according to the Rome III criteria, and to evaluate the sensitivity of the simplified Rome II criteria. A total of 923 patients were enrolled. Demographic and clinical data, including GERD symptoms, were recorded. The mean age was 60.7 years and 646 (70%) were male. Data from the registry were found to be adequate. The prevalence of the different symptoms was: heartburn: 80%; heartburn and regurgitation: 85%; regurgitation: 72%; and dysphagia: 14.7%. The prevalence of at least one daily symptom (wheezy chest, and/or cough) was 31%. The simplified Rome II criteria were positive in 270 patients (29.4%). According to the Rome III criteria, the diagnosis of GERD was in 452 patients (49.2%). For diagnosing a suspected case of
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