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What is the format of date when I generate using a database call?
Lets say I have this line of code in a class:
q.date = DateTime.Today
How is that date formatted for SQL? If I just do:
DateTime.Today
I am sure I get a different date.
A:
It’s not an SQL-server date but a C# DateTime.
You can see the format in the documentation DateTime.ToString
Size-controlled synthesis and in vitro and in vivo evaluation of MMP-2/9 specific gold nanoparticles by MHA functionalized silica-based nanocomposite.
Gold nanoparticles synthesized by seed-mediated growth method with spherical geometry and size ranging between 20 and 50nm were immobilized onto hydroxyl amine functionalized mesoporous silica nanospheres via the formation of covalent bonds. The resultant nanocomposite was characterized for size and size distribution. The zeta potential of nanocomposite suggested the stability in physiological conditions. The role of nanocomposite in matrix metalloproteinases (MMP) inhibition was evaluated by gelatin zymography. The results showed an increase in inhibitory potential of nanocomposite in comparison to free metal nanoparticles due to the biocompatible nature of mesoporous silica. This inhibition was specific for gelatinases MMP-2 and MMP-9 without any change in the activity of other MMPs. Further, to understand the in vivo specificity and kinetics of nanocomposite, we administered intravenously radiolabeled nanocomposite to male Wistar rats, and the tracer was recovered from major organs at different time intervals. The in vivo specificity and kinetics are very well correlated with the in vitro findings. The results of the present study demonstrated the effectiveness of our synthesized nanocomposite as a potential candidate in MMPs inhibition therapy and in vivo imaging and drug delivery.Q:
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